|
Sunday May 15th 2011
|
|
16:00
|
Welcome
|
H. Katinger, BOKU Vienna
N. Borth, BOKU Vienna
|
|
Session I: Cell stability and differentiation
|
|
16:10
|
Chair´s Introduction
|
T. von Zglinicki, U Newcastle, UK
|
|
16:15
|
Molecular mechanisms of cellular senescence
|
F. d´Adda di Fagagno, IFOM, Italy
|
|
16:45
|
MicroRNA-31: an inhibitor of osteogenic differentiation of mesenchymal stem cells
|
J. Grillari, BOKU Vienna
|
|
17:15
|
Immortalized Endothelial Cell Lines
|
T. May, HZI Braunschweig, Germany
|
|
17:35
|
Senescence-associated genes and their implication in the induction of cellular senescence
|
M. Udono, Kyushu University
|
|
Keynote Lecture I:
|
|
17:50
|
The Antibody Revolution
|
G. Winter, MRC, UK
|
|
18:30 Trader´s Reception
|
|
Monday May 16th 2011
|
|
Session II: Cells as Therapies and Stem Cells
|
|
09:00
|
Chairs Introduction
|
J. Friedl, Medical University Vienna
H. Hauser, HZI, Germany
|
|
09:05
|
Critical role of IFNg for the production of highly immunogenic dendritic cell-derived exosomes
|
N. Chaput, Institute Gustave Roussy, France
|
|
09:35
|
ATMPs – The Regulatory Perspective
|
I. Reischl, AGES Pharmed, Austria
|
|
10:05
|
Cell-based medicinal products and the development of GMP-compliant processes and manufacturing
|
L. Romagnoli, Areta International, Italy
|
|
10:25 Coffee Break
|
|
11:00
|
Ultra High Yield Manufacture of Red Blood Cells in Fully Defined Animal Component Free Medium
|
N. Timmins, U Queensland, Australia
|
|
11:20
|
Road to the clinics and in vitro disease modeling using iPSCs: Wilson's Disease
|
M. Esteban, Chinese Academy of Science
|
|
11:50
|
Manufacturing Process Optimization Strategies for Autologous Active Cellular Immunotherapies (ACIs)
|
C. Ramsborg, Dendreon Corporation, USA
|
|
12:20
12:20
|
Poster Session A and Lunch
General Assembly
|
Main Lecture Hall
|
|
Session III: Cellular Mechanisms of protein synthesis, processing & secretion
|
|
15:00
|
Chair´s Introduction
|
R. Jefferis, University of Birmingham
M. Butler, University of Manitoba
|
|
15:05
|
Quality control of immunoglobulin biosynthesis: life and death decisions
|
L. Hendershot, St. Jude´s Hospital, USA
|
|
15:35
|
Golgi Biogenesis in a protozoan parasite
|
G. Warren, Max Perutz Laboratories, Austria
|
|
16:05 Coffee Break
|
|
16:20
|
Impact of Glycosylation and Sialylation on Ion Channels and the Nervous System
|
D. Baycin Hizal, Johns Hopkins U, USA
|
|
16:40
|
Antibody Disulfide Bond Reduction in CHO Cell Culture Processes
|
M. Laird, Genentech, USA
|
|
16:50
|
Evaluation of Impact of Cell Culture Process Conditions on Consistency of Trisulfide vs Native Disulfides Linkages in an IgG1 Molecule
|
R. Kshirsagar, Biogen Idec, USA
|
|
17:00
|
Using Intact Protein Accurate Mass Data and Differential Gel Electrophoresis (DIGE) to Assess Clonal Difference in High-Mannose Oligosaccharide Content in Recombinant Humanized IgG Producing Chinese Hamster Ovary Cells
|
N. Lin, SAFC, USA
|
|
17:20
|
Poster Session B and drinks
|
|
|
Tuesday May 17th 2011
|
|
Session IV: Biopharmaceutics and Vaccine Production
|
|
9:00
|
Chair´s Introduction
|
O. Kistner, Baxter Austria
H. Katinger, BOKU Vienna
|
|
9:05
|
Protein Pharmaceuticals: Future State
|
M. Slikowski, Genentech, USA
|
|
9:35
|
Recombinant antibody mixtures: optimization of cell line generation and single-batch manufacturing processes
|
S. Rasmussen, Symphogen, Denmark
|
|
9:55
|
High yield antibody production using a perfusion process in a disposable WAVE bioreactor
|
C. Kaisermayer, GE Healthcare
|
|
10:15
|
Highly efficient, chemically defined and fully scalable production of host-restricted pox viruses
|
I. Jordan, ProBioGen, Germany
|
|
10:35 Coffee Break
|
|
11:20
|
Vaccine Production
|
J. Aunins, Merck USA
|
|
11:50
|
Fluorescence-based tools to support biopharmaceutical process development
|
A. Teixeira, IBET, Portugal
|
|
12:10
|
Detection and Remediation of a Vesivirus 2117 Related Contamination in Large-Scale CHO Cell Cultures
|
W. Zhou, Genzyme Corporation, USA
|
|
12:30
|
Posters and Lunch, ESACT General Assembly
|
|
15:00
|
Outing to Schloss Hof
|
|
Wednesday May 18th 2011
|
|
Session V: Understanding Complex Interactions and Cell Engineering
|
|
9:00
|
Chair´s Introduction
|
Martin Fussenegger, ETH Zurich
|
|
9:05
|
Integrated Single-Cell Analysis
|
Ch. Love, MIT, USA
|
|
9:35
|
Biosynthetic Pathway Deflection – a new engineering approach and efficient strategy for ADCC enhancement
|
V. Sandig, ProbioGen, Germany
|
|
9:55
|
Improved cell line selection through in situ metabolic profiling and offline product analysis
|
A. Behjousiar, Imperial College London, UK
|
|
10:10
|
Coffee Break
|
|
11:00
|
Influenza Viruses and Host Cell signaling - from molecular mechanisms to novel antiviral approaches
|
S. Ludwig, U Münster, Germany
|
|
11:30
|
Towards rational engineering of cells: Recombinant Gene Expression in Defined Chromosomal Loci
|
D.Wirth, HZI Braunschweig, Germany
|
|
11:50
|
Establishment of a large scale functional screening method for microRNAs in Chinese hamster ovary cells
|
M. Hackl, BOKU Vienna, Austria
|
|
12:05
|
Posters and Lunch
|
|
Short Poster Presentations
Chairs: Poster Committee
|
|
14:00
|
Chair´s Introduction and Explanation of Voting Procedure
|
|
|
14:10
|
Short Poster presentations
|
|
|
15:20
|
Coffee Break
|
|
15:50
|
Short Poster presentations
|
|
|
17:00
|
Collection of votes
|
|
|
Keynote Lecture I:
|
|
17:10
|
The Chemistry of Large Numbers
|
Richard Lerner, The Scripps Research Institute, USA
|
|
19:00
|
Gala Dinner at the Prater Galeries
|
